College Football Odds Week 12: Louisville vs Miami Lines, Spreads, Betting Trends

Matchup Spread Total Moneyline
Miami vs
Louisville
+1.5 (-120)
-1.5 (-102)
o46.5 (-105)
u46.5 (-115)
-110
-110

Louisville looks to remain in the Top 10 with a win at Miami in Week 12 of college football. Betting odds see the Cardinals as 1.5-point road favorites against the Hurricanes. Coverage begins from Hard Rock Stadium on Saturday, November 18 at 12:00 p.m. ET on ABC.

Here's everything you need to know about the college football odds for Week 12 Louisville vs Miami the opening lines, spreads, betting trends and more. Check back regularly for updates and use our BetMGM bonus code to get the most out of your action.

No. 9 Louisville vs Miami Odds

Miami tries to get on track against Louisville at home. (Getty)
  • Opening point spread: Louisville -1.5
  • Opening moneyline: Louisville -115/Miami -106
  • Opening total: Over/Under 47points scored
  • Time: Noon ET Saturday (ABC)

UPDATE 2 P.M. ET MONDAY: Louisville (9-1 SU/5-4-1 ATS) held a 14-0 halftime lead over Virginia, then gave it all back and then some in the third quarter. The Cards trailed 21-14 entering the fourth quarter, but rallied for a 31-24 victory.

Still, Louisville fell far short of covering as 20.5-point chalk.

Meanwhile, Miami's 4-0 SU start – which would've been 5-0 if not for a historically dumb coaching decision vs. Georgia Tech – is now a distant memory. The Hurricanes are 2-4 SU and ATS in their last six games to stand 6-4 SU/5-5 ATS on the season.

In Week 11, Miami hung around at unbeaten Florida State, but didn't have enough in a 27-20 loss getting 14.5 points.

TwinSpires Sportsbook opened Louisville -1.5 vs. Miami, and the number is up to -2 in the college football Week 12 odds market. The Cardinals are getting 60% of early spread bets/69% of early spread money.

"It's a mix of sharp and public play on Louisville. We're going to need Miami, with all of the Louisville handle we see each week," TwinSpires director of retail sports Zachary Lucas said.

Indeed, TwinSpires has a big footprint in Kentucky and draws plenty of Cardinals and Kentucky Wildcats action.

The total bumped from 47 to 47.5 in the early going, with 57% of tickets/58% of money on the Over.

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Click here for Vegas Insider senior reporter Patrick Everson's full College Football Odds Week 12 Report containing spreads, lines, and trends for every Top 25 matchup.